Professor Gu Yan is the director of general surgery (comprises of gastrointestinal surgery, breast and thyroid surgery, hepatobiliary and pancreatic surgery, hernia and abdominal wall surgery, and bariatric and metabolic surgery) at the Huadong Hospital Affiliated to Fudan University. He has commenced the teaching of undergraduate and graduate courses such as 'Surgery, Obesity Medicine, and Obesity Therapy'. He is the Chief Editor of three monographs, including ' Practical of Obesity and Metabolic Surgery', 'Practical of Abdominal Wall Surgery', and 'Early Diagnosis and Treatment of Colorectal Cancer'. Associate editor of one monograph, 'Surgical Diagnosis and Differential Diagnosis'. Participated in the editing of 13 other monographs; Professor Gu Yan led the development of 9 Chinese consensus and guidelines, including 'Chinese expert consensus on adult ventral abdominal wall defect repair and reconstruction', 'Chinese expert consensus on laparoscopic sleeve gastrectomy as ambulatory surgery (2021 version)', and 'Chinese expert consensus on surgical treatment of obesity combined with abdominal wall hernia (2021 version)'. Participated in the development of 25 consensus and guidelines; Responsible for over 30 national and provincial level scientific research projects, including 6 National Natural Science Foundation projects; Nurture more than 50 postdoctoral, doctoral and master's students. Over 200 papers have been published in domestic and international journals as lead author or corresponding author, which includes 67 SCI papers. Received the third prize of Huaxia Science and Technology Progress Award and the first prize of Shanghai Science and Technology Progress Award.

•   1989 – Bachelor
  Nanjing Railway Medical College (now known as Southeast University School of Medicine)

•   1996 – Ph.D.
  Nanjing Railway Medical College (now known as Southeast University School of Medicine)

•   2005 – 2006
  Teaching and Research Position UCLA U.S.A.

• China International Exchange and Promotive Association for Medical and Health Care (CPAM) – Board of Trustee

• China International Exchange and Promotive Association for Medical and Health Care General Surgery Branch – Vice Chairman

• China Hernia Society - Committee Member

• Chinese Medical Doctor Association Hernia and Abdominal Wall Surgery Branch – Special Committee

• Chinese Medical Doctor Association Obesity and Diabetes Branch - Committee Member

• Chinese Research Hospital Association Surgery for Obesity and Diabetes Branch – Standing Committee Member

• Chinese Association of Rehabilitation Medicine Bariatric and Metabolic Surgery Branch - Standing Committee Member

• National Health Commission Capacity Building and Continuing Education Surgery Branch - Special Committee

• Chinese Society for Metabolic & Bariatric Surgery - Committee Member

• Chinese Journal of Hernia and Abdominal Wall Surgery – Past deputy Editor-in-Chief

• Served as the Executive Editorial Board Member and Editorial Board Member of multiple journals such as the Chinese Journal of Obesity and Metabolic Diseases.              

1. Song ZC, Yang DC, Hu QX, Wang YM, Zhang HG, Dong WP, Yang JJ, Gu Y. Reconstruction of Abdominal Wall Defect with Composite Scaffold of 3D Printed ADM/PLA in a Rat Model. Macromolecular Bioscience. 2023;6:e2200521. doi: 10.1002/mabi.202200521.

2. Jason Widjaja, Jianjun Yang, Yan Gu. The Need for Better Clarifcation Regarding Hiatal Hernia Observed During Bariatric Surgery. Obesity Surgery 2022, doi.org/10.1007/s11695-022-06393-2.

3. Jason Widjaja, Yuxiao Chu, Jianjun Yang, Jian Wang, Yan Gu. Can we abandon foregut exclusion for an ideal and safe metabolic surgery? Frontiers in Endocrinology (Lausanne) ,2022;13:1014901.

4. Qingxi Hu, Runsheng Lu, Suihong Liu, Yakui Liu, Yan Gu, Haiguang Zhang. 3D Printing GelMA/PVA Interpenetrating Polymer Networks Scaffolds Mediated with CuO Nanoparticles for Angiogenesis. Macromolecular Bioscience. 2022 Jul 29;e2200208. doi: 10.1002/mabi.202200208.

5. Hu QX, Wu JJ, Zhang HG, Dong WP, Gu Y, Liu SH. Designing Double-Layer Multi-Material Composite Patch Scaffold with Adhesion Resistance for Hernia Repair. Macromolecular Bioscience. 26:e2100510.doi: 10.1002/mabi.202100510.

6. Liu Y, Hu Q, Dong W, Liu S, Zhang H, Gu Y. Alginate/Gelatin-based Hydrogel with Soy Protein/ peptide Powder for 3D Printing Tissue-engineering Scaffolds to Promote. Angiogenesis. Macromolecular Bioscience. e2100413. doi: 10.1002/mabi.202100413

7. Wenpei Dong, Zhicheng Song, Suihong Liu, Ping Yu, Zhipeng Shen, Jianjun Yang, Dongchao Yang, Qinxi Hu, Haiguang Zhang, Yan Gu. Adipose-Derived Stem Cells Based on Electrospun Biomimetic Scaffold Mediated Endothelial Differentiation Facilitating Regeneration and Repair of Abdominal Wall Defects via HIF-1α/VEGF Pathway. Frontiers in Bioengineering and Biotechnology. 2021 Jul 7;9:676409.doi: 10.3389/fbioe.2021.676409.

8. Wu JG, Cai HJ, Shan HY, Pan CP, Xu X, Dong WP, Yu JW, Gu Y. Histone Methyltransferase SETD1A Induces Epithelial-Mesenchymal Transition to Promote Invasion and Metastasis Through Epigenetic Reprogramming of Snail in Gastric Cancer. Frontiers in Cell and Developmental Biology 2021;9.

9. Song Z, Yang D, Song H, Dong W, Wu J, Yang J, Gu Y. Surgical treatment strategy for locally advanced colorectal cancer with abdominal wall invasion. Annals of Translational Medicine 2021;9(10):874. doi: 10.21037/atm-21-2094.

10. Wu J, Chai H, Li F, Ren Q, Gu Y. SETD1A augments sorafenib primary resistance via activating YAP in hepatocellular carcinoma. Life Sciences 2020;260:118406.

11. Zhu D, Xia J, Gu Y, Lin J, Ding K, Zhou B, Liang F, Liu T, Qin C, Wei Y, Ren L, Zhong Y, Wang J, Yan Z, Cheng J, Chen J, Chang W, Zhan S, Ding Y, Huo H, Liu F, Sun J, Qin X, Xu J. Preoperative hepatic and regional arterial chemotherapy in patients who underwent curative colorectal cancer resection: a prospective, multi-center, randomized controlled trial. Annals of Surgery 2020.

12. Gu Y, Wang P. Li HY, Tian W, Tang JX. Chinese expert consensus on adult ventral abdominal wall defect repair and reconstruction. American Journal of Surgery 2021;222(1):86-98.

13. Yang Z, Song Z, Nie X, Guo K, Gu Y. A smart scaffold composed of three-dimensional printing and electrospinning techniques and its application in rat abdominal wall defects. Stem Cell Research & Therapy. 2020 Dec 10;11(1):533.

14. Song ZC, Yang DC, Wang YP, Bu XM, Yang JJ, Wu JG, Nie X, Song H, Gu Y. Three-dimensional visualization and measurement of myopectineal orifice in non-inguinal hernia patients. Surgical and Radiologic Anatomy 2020; 42(11), 1315-1322.

15. Yang DC, Song ZC, Lin YJ, Dong WP, Fu SJ, Yang JJ, Zhang PH, Gu Y. Prevention of intestinal adhesion and regeneration of abdominal wall tissue with meshes containing an electrostatically spun acellular dermal matrix (ADM)/silk fibroin (SF) fiber composite polypropylene mesh. Journal of the Mechanical Behavior of Biomedical Materials 2020;112: 104087.

16. Wu JG, Cai HJ, Xu X, Yu JW, Gu Y. Histone methyltransferase SETD1A interacts with HIF1a to enhance glycolysis and promote cancer progression in gastric cancer. Molecular Oncology 2020;14(6):1397-1409.

17. Wu J, Tian B, Yang J, Huo H, Song Z, Yu J, Gu Y. Reduction of Hip2 suppresses gastric cancer cell proliferation, migration, invasion and tumorigenesis. Translational Cancer Research 2020:9(2):774-785.

18. Dongchao Yang, Zhicheng Song, Jiali Shen, Heng Song, Jianjun Yang, Peihua Zhang & Yan Gu. Regenerated silk fibroin (RSF) electrostatic spun fibre composite with polypropylene mesh for reconstruction of abdominal wall defects in a rat model. Artificial cells, nanomedicine, and biotechnology 2020;48(1): 425–434.

19. Zhang B, Wu J, Cai Y, Luo M, Wang B, Gu Y. TCF7L1 indicates prognosis and promotes proliferation through activation of Keap1/NRF2 in gastric cancer. Acta Biochimica et Biophysica Sinica. 2019 Apr 1;51(4):375-385.

20. Jugang Wu, Jianjun Yang, Haizhong Huo, Zhicheng Song, Xin Nie, Yan Gu. Surgical strategies for abdominal wall invasion and implantation of colorectal cancer. International journal of clinical and experimental medicine. 2019;12(9):11746-11753 (IF=0.181)

21. Zhang B, Wu J, Cai Y, Luo M, Wang B, Gu Y. AAED1 modulates proliferation and glycolysis in gastric cancer. Oncology Reports. 2018;40(2):1156-1164.

22. Yang Z, Song Z, Nie X, Yang J, Zhu C, Guo K, Gu Y. Characteristic properties of muscular-derived extracellular matrix and its application in rat abdominal wall defects. Regenerative Medicine 2018; 13(5):503-517.

23. Z Song, D Yang, J Yang, X Nie, J Wu, H Song, Y Gu. Abdominal wall reconstruction following resection of large abdominal aggressive neoplasms using tensor fascia lata flap with or without mesh reinforcement. Hernia 2018;22(2):333-341.

24. Chen YW, Yang JJ, Nie X, Song ZC, Gu Y. Effects of Bariatric Surgery on Change of Brown Adipocyte Tissue and Energy Metabolism in Obese Mice. Obesity surgery 2018;28(3):820-830.